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Noorul Huda

Diels-Alder reaction (summarised)

Diels-Alder reaction

Also known as: Diels-Alder cycloaddition


 The Diels-Alder reaction is an organic reaction used to convert a conjugated diene and a dienophile to a cyclic olefin under thermal conditions. This is a concerted process where bonds are forming and breaking at the same time and the reaction belongs to a class of reactions termed "cycloaddition". The Diels-Alder reaction is by far the most famous 'name reaction' and it is extensively used in natural product synthesis. When predicting the regiochemistry and stereochemistry of the product, things to consider are the electronic character of the substitutes on the diene and dienophile, the partial charges formed, and the orientation of the starting materials when they approach each other.


Kinetics of the Reaction:

The Diene must be in the s-cis conformation for the reaction to occur.



Molecular Orbital Theory:

Molecular Orbitals with the same sign must overlap during the cycloaddition.


Regiochemistry of the Diels-Alder reaction can be predicted using partial charges.


Stereochemistry of the Diels-Alder reaction can be predicted by the "Endo rule".




Using the same rationale as previously, the outcome of the following reactions can be explained.


  Also Visit: Three Trends that affect boiling point of organic compounds.

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Noorul Huda

About Noorul Huda -

A chemist, a teacher and a passionate blogger. Currently pursuing his PhD from School of Chemistry, University of Hyderabad is creative head of this blog and lives with a motto of teaching what he knows and exploring what he don't.

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24 October 2016 at 04:38 delete

i liked it. can you pls provide PDF of this

31 October 2017 at 04:43 delete

Recently my students were having some problems in the same topics defined in this post, but just then I came up with this post and had a really good help!

Noorul Huda
1 November 2017 at 21:34 delete

Thank You... It gives lots of motivation to know that my work is helping you people... Thanks for letting us know...